Police allege the suspects forced their way into a home, assaulted the residents and killed two kittens by stomping on them.
Police say officers responding to a disturbance call (on Eagle Ave.) early Saturday morning were confronted by a drunken male who started punching their cruiser.
They say the man then turned on officers, and after being placed in a cruiser kicked out its rear window.
The man is also accused of damaging a cell at the Brantford police station.
Twenty-seven-year-old Justin Webber of Brantford is facing numerous charges including two counts of killing or injuring an animal, break and enter, assault and breach of probation.
Twenty-nine-year-old James Carpenter, also of Brantford, is facing a slew of charges including causing a disturbance by being drunk, assault police and resisting arrest.
The two remain in custody with a court appearance scheduled for Tuesday.
Police, meantime, say they're looking for a third suspect in the case.