A 46-year-old woman was charged with impaired driving, while a 29-year-old man registered in the warn range during a roadside breath test.
Both drivers were among the 100 checked during the Festive RIDE campaign, set up on Bancroft Drive at Shelbourne Street and Regent Street at Telstar Avenue.
Officers also doled out eight Highway Traffic Act offences.
The RIDE program is aimed at reducing property damage, injuries and death caused by impaired driving. Officers will be setting up check points every night for the month of December.